Author:
Gibson Graham C.,Woody Spencer,James Emily,Weldon Minda,Fox Spencer J.,Meyers Lauren Ancel,Bhavnani Darlene
Abstract
AbstractCommunities worldwide have used vaccines and facemasks to mitigate the COVID-19 pandemic. When an individual opts to vaccinate or wear a mask, they may lower their own risk of becoming infected as well as the risk that they pose to others while infected. The first benefit–reducing susceptibility–has been established across multiple studies, while the second–reducing infectivity–is less well understood. Using a new statistical method, we estimate the efficacy of vaccines and facemasks at reducing both types of risks from contact tracing data collected in an urban setting. We find that vaccination reduced the risk of onward transmission by 40.7% [95% CI 25.8–53.2%] during the Delta wave and 31.0% [95% CI 19.4–40.9%] during the Omicron wave and that mask wearing reduced the risk of infection by 64.2% [95% CI 5.8–77.3%] during the Omicron wave. By harnessing commonly-collected contact tracing data, the approach can broadly provide timely and actionable estimates of intervention efficacy against a rapidly evolving pathogen.
Funder
Council of State and Territorial Epidemiologists
Publisher
Springer Science and Business Media LLC
Reference43 articles.
1. Sheikh, A., Robertson, C. & Taylor, B. BNT162b2 and ChAdOx1 nCoV-19 vaccine effectiveness against death from the delta variant. N. Engl. J. Med. 385(23), 2195–2197 (2021).
2. Braeye, T. et al. Vaccine effectiveness against infection and onwards transmission of COVID-19: Analysis of belgian contact tracing data, January-June 2021. Vaccine 39(39), 5456–5460 (2021).
3. Oon, T. N. et al. Impact of delta variant and vaccination on SARS-CoV-2 secondary attack rate among household close contacts. Lancet Reg. Health West Pac. 17, 100299 (2021).
4. Yair, G. et al. Waning immunity after the BNT162b2 vaccine in israel. N. Engl. J. Med. 5, 789 (2021).
5. Patrick, T. et al. BNT162b2 and mRNA-1273 COVID-19 vaccine effectiveness against the SARS-CoV-2 delta variant in qatar. Nat. Med. 5, 968 (2021).
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