Computational affinity maturation of camelid single-domain intrabodies against the nonamyloid component of alpha-synuclein-Reference-Cited by-同舟云学术

Computational affinity maturation of camelid single-domain intrabodies against the nonamyloid component of alpha-synuclein

Published:2018-12 Issue:1 Volume:8 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Mahajan Sai Pooja,Meksiriporn Bunyarit,Waraho-Zhmayev Dujduan,Weyant Kevin B.,Kocer Ilkay,Butler David C.,Messer Anne,Escobedo Fernando A.,DeLisa Matthew P.^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-018-35464-7.pdf

Reference76 articles.

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3. Stefanis, L. Alpha-Synuclein in Parkinson’s disease. Cold Spring Harb Perspect Med 2, a009399 (2012).

4. Wong, Y. C. & Krainc, D. Alpha-synuclein toxicity in neurodegeneration: mechanism and therapeutic strategies. Nat Med 23, 1–13 (2017).

5. Bhatt, M. A., Messer, A. & Kordower, J. H. Can intrabodies serve as neuroprotective therapies for Parkinson’s disease? Beginning thoughts. J Parkinsons Dis 3, 581–91 (2013).

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