Pharmacokinetics of anti-infectious reagents in silkworms
Author:
Funder
Takeda Science Foundation
MEXT | Japan Society for the Promotion of Science
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-019-46013-1.pdf
Reference28 articles.
1. Kaito, C., Akimitsu, N., Watanabe, H. & Sekimizu, K. Silkworm larvae as an animal model of bacterial infection pathogenic to humans. Microb Pathog 32, 183–190, https://doi.org/10.1006/mpat.2002.0494 (2002).
2. Hamamoto, H. et al. Quantitative evaluation of the therapeutic effects of antibiotics using silkworms infected with human pathogenic microorganisms. Antimicrob Agents Chemother 48, 774–779, https://doi.org/10.1128/aac.48.3.774-779.2004 (2004).
3. Hamamoto, H. et al. Lysocin E is a new antibiotic that targets menaquinone in the bacterial membrane. Nat Chem Biol 11, 127–133, https://doi.org/10.1038/nchembio.1710 (2015).
4. Nakamura, I. et al. Discovery of a new antifungal agent ASP2397 using a silkworm model of Aspergillus fumigatus infection. J Antibiot (Tokyo) 70, 41–44, https://doi.org/10.1038/ja.2016.106 (2017).
5. Paudel, A. et al. A Novel Spiro-Heterocyclic Compound Identified by the Silkworm Infection Model Inhibits Transcription in Staphylococcus aureus. Front Microbiol 8, 712, https://doi.org/10.3389/fmicb.2017.00712 (2017).
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