Whole-genome sequencing reveals nosocomial Clostridioides difficile transmission and a previously unsuspected epidemic scenario
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Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-019-43464-4.pdf
Reference47 articles.
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2. Martin, J. S., Monaghan, T. M. & Wilcox, M. H. Clostridium difficile infection: epidemiology, diagnosis and understanding transmission. Nat Rev Gastroenterol Hepatol 13, 206–216, https://doi.org/10.1038/nrgastro.2016.25 (2016).
3. Davies, K. A. et al. Underdiagnosis of Clostridium difficile across Europe: the European, multicentre, prospective, biannual, point-prevalence study of Clostridium difficile infection in hospitalised patients with diarrhoea (EUCLID). Lancet Infect Dis 14, 1208–1219, https://doi.org/10.1016/S1473-3099(14)70991-0 (2014).
4. Indra, A. et al. Characterization of Clostridium difficile isolates using capillary gel electrophoresis-based PCR ribotyping. J Med Microbiol 57, 1377–1382, https://doi.org/10.1099/jmm.0.47714-0 (2008).
5. Fawley, W. N. et al. Development and validation of an internationally-standardized, high-resolution capillary gel-based electrophoresis PCR-ribotyping protocol for Clostridium difficile. PLOS One 10, e0118150, https://doi.org/10.1371/journal.pone.0118150 (2015).
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