NEC is likely a NETs dependent process and markers of NETosis are predictive of NEC in mice and humans
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-31087-0.pdf
Reference41 articles.
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2. Caplan, M. S. Neonatal necrotizing enterocolitis. Introduction. Semin Perinatol 32, 69, https://doi.org/10.1053/j.semperi.2008.02.001 (2008).
3. Leaphart, C. L. et al. A Critical Role for TLR4 in the Pathogenesis of Necrotizing Enterocolitis by Modulating Intestinal Injury and Repair. The Journal of Immunology 179, 4808–4820, https://doi.org/10.4049/jimmunol.179.7.4808 (2007).
4. Nanthakumar, N. N., Fusunyan, R. D., Sanderson, I. & Walker, W. A. Inflammation in the developing human intestine: A possible pathophysiologic contribution to necrotizing enterocolitis. Proceedings of the National Academy of Sciences 97, 6043–6048, https://doi.org/10.1073/pnas.97.11.6043 (2000).
5. Good, M. et al. Breast milk protects against the development of necrotizing enterocolitis through inhibition of Toll Like Receptor 4 in the intestinal epithelium via activation of the epidermal growth factor receptor. Mucosal Immunol 8, 1166–1179 (2015).
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