Metformin increases gut multidrug resistance genes in type 2 diabetes, potentially linked to Escherichia coli
Author:
Funder
National Research Foundation of Korea
Korea National Institute of Health
Publisher
Springer Science and Business Media LLC
Link
https://www.nature.com/articles/s41598-024-72467-z.pdf
Reference37 articles.
1. Ahmad, E. et al. Where does metformin stand in modern day management of type 2 diabetes?. Pharmaceuticals 13(12), 427 (2020).
2. Zhang, Q. & Hu, N. Effects of metformin on the gut microbiota in obesity and type 2 diabetes mellitus. Diabetes Metab. Syndr. Obes. 13, 5003–5014 (2020).
3. Silamiķele, L. et al. Metformin strongly affects gut microbiome composition in high-fat diet-induced type 2 diabetes mouse model of both sexes. Front. Endocrinol. 12, 626359 (2021).
4. He, D. et al. Metformin reduces blood glucose in treatment-naive type 2 diabetes by altering the gut microbiome. Can. J. Diabetes 46(2), 150–156 (2022).
5. Ezzamouri, B. et al. Metabolic modelling of the human gut microbiome in type 2 diabetes patients in response to metformin treatment. NPJ Syst. Biol. Appl. 9(1), 2 (2023).
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