The role of oxidative stress in the crosstalk between leptin and mineralocorticoid receptor in the cardiac fibrosis associated with obesity-Reference-Cited by-同舟云学术

The role of oxidative stress in the crosstalk between leptin and mineralocorticoid receptor in the cardiac fibrosis associated with obesity

Published:2017-12 Issue:1 Volume:7 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Gutiérrez-Tenorio Josué,Marín-Royo Gema,Martínez-Martínez Ernesto,Martín Rubén,Miana María,López-Andrés Natalia,Jurado-López Raquel,Gallardo Isabel,Luaces María,San Román José Alberto,González-Amor María,Salaices Mercedes,Nieto María Luisa,Cachofeiro Victoria

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-017-17103-9.pdf

Reference42 articles.

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2. Eschalier, R. et al. Features of cardiac remodeling, associated with blood pressure and fibrosis biomarkers, are frequent in subjects with abdominal obesity. Hypertension 63, 740–746, https://doi.org/10.1161/HYPERTENSIONAHA.113.02419 (2014).

3. Cavalera, M., Wang, J. & Frangogiannis, N. G. Obesity, metabolic dysfunction, and cardiac fibrosis: pathophysiological pathways, molecular mechanisms, and therapeutic opportunities. Transl Res 164, 323–335, https://doi.org/10.1016/j.trsl.2014.05.001 (2014).

4. Kosmala, W., Przewlocka-Kosmala, M., Szczepanik-Osadnik, H., Mysiak, A. & Marwick, T. H. Fibrosis and cardiac function in obesity: a randomised controlled trial of aldosterone blockade. Heart 99, 320–326, https://doi.org/10.1136/heartjnl-2012-303329 (2013).

5. Huby, A. C. et al. Adipocyte-Derived Hormone Leptin Is a Direct Regulator of Aldosterone Secretion, Which Promotes Endothelial Dysfunction and Cardiac Fibrosis. Circulation 132, 2134–2145, https://doi.org/10.1161/CIRCULATIONAHA.115.018226 (2015).

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