Author:
Nor Norefrina Shafinaz Md,Yip Chee Wai,Ibrahim Nazlina,Jaafar Mohd Hasni,Rashid Zetti Zainol,Mustafa Norlaila,Hamid Haris Hafizal Abd,Chandru Kuhan,Latif Mohd Talib,Saw Phei Er,Lin Chin Yik,Alhasa Kemal Maulana,Hashim Jamal Hisham,Nadzir Mohd Shahrul Mohd
Abstract
AbstractThe rapid spread of the SARS-CoV-2 in the COVID-19 pandemic had raised questions on the route of transmission of this disease. Initial understanding was that transmission originated from respiratory droplets from an infected host to a susceptible host. However, indirect contact transmission of viable virus by fomites and through aerosols has also been suggested. Herein, we report the involvement of fine indoor air particulates with a diameter of ≤ 2.5 µm (PM2.5) as the virus’s transport agent. PM2.5 was collected over four weeks during 48-h measurement intervals in four separate hospital wards containing different infected clusters in a teaching hospital in Kuala Lumpur, Malaysia. Our results indicated the highest SARS-CoV-2 RNA on PM2.5 in the ward with number of occupants. We suggest a link between the virus-laden PM2.5 and the ward’s design. Patients’ symptoms and numbers influence the number of airborne SARS-CoV-2 RNA with PM2.5 in an enclosed environment.
Funder
Universiti Kebangsaan Malaysia
Publisher
Springer Science and Business Media LLC
Reference35 articles.
1. Liu, Y. et al. Aerodynamic analysis of SARS-CoV-2 in two Wuhan hospitals. Nature. https://doi.org/10.1038/s41586-020-2271-3 (2020).
2. Chan, J. F. W. et al. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. Lancet 395, 514–523 (2020).
3. Huang, C. et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 395, 497–506 (2020).
4. World Health Organization. Infection prevention and control of epidemic- and pandemic-prone acute respiratory infections in health care. (World Health Organization, Geneva, 2014).
5. Ong, S. W. et al. Air, surface environmental, and personal protective equipment contamination by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from a symptomatic patient. JAMA 16, 1610–1612 (2020).
Cited by
91 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献