Single Nucleotide Polymorphisms in the G-Protein Coupled Receptor Kinase 5 (GRK5) Gene are associated with Plasma LDL-Cholesterol Levels in Humans-Reference-Cited by-同舟云学术

Single Nucleotide Polymorphisms in the G-Protein Coupled Receptor Kinase 5 (GRK5) Gene are associated with Plasma LDL-Cholesterol Levels in Humans

Published:2018-05-17 Issue:1 Volume:8 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Lutz Stefan Z.,Falcenberg Mathias,Machicao Fausto,Peter Andreas,Kächele Martin,Randrianarisoa Elko,Lehn-Stefan Angela,Wagner Robert^ORCID,Machann Jürgen,Schick Fritz,Heni Martin^ORCID,Ullrich Axel,Fritsche Andreas,Stefan Norbert,Häring Hans-Ulrich,Staiger Harald,Kantartzis Konstantinos

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-018-26055-7.pdf

Reference33 articles.

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2. Homan, K. T. et al. Identification and structure-function analysis of subfamily selective G protein-coupled receptor kinase inhibitors. ACS Chem. Biol 10, 310–319 (2015).

3. Ribas, C. et al. The G protein-coupled receptor kinase (GRK) interactome: role of GRKs in GPCR regulation and signaling. Biochim. Biophys. Acta 1768, 913–922 (2007).

4. Sorriento, D. et al. The G-protein-coupled receptor kinase 5 inhibits NFkappaB transcriptional activity by inducing nuclear accumulation of IkappaB alpha. Proc. Natl. Acad. Sci. USA 105, 17818–17823 (2008).

5. Chen, Y. et al. GRK5 promotes F-actin bundling and targets bundles to membrane structures to control neuronal morphogenesis. J. Cell Biol 194, 905–920 (2011).

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