Crystal structure of an L chain optimised 14F7 anti-ganglioside Fv suggests a unique tumour-specificity through an unusual H-chain CDR3 architecture
Author:
Funder
Norges Forskningsråd (Research Council of Norway)
Science Foundation Ireland (SFI)
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-28918-5.pdf
Reference64 articles.
1. Mellman, I., Coukos, G. & Dranoff, G. Cancer immunotherapy comes of age. Nature 480, 480–489, https://doi.org/10.1038/nature10673 (2011).
2. Drake, C. G., Lipson, E. J. & Brahmer, J. R. Breathing new life into immunotherapy: review of melanoma, lung and kidney cancer. Nat Rev Clin Oncol 11, 24–37, https://doi.org/10.1038/nrclinonc.2013.208 (2014).
3. Farkona, S., Diamandis, E. P. & Blasutig, I. M. Cancer immunotherapy: the beginning of the end of cancer? BMC Med 14, 73, https://doi.org/10.1186/s12916-016-0623-5 (2016).
4. Scott, A. M., Allison, J. P. & Wolchok, J. D. Monoclonal antibodies in cancer therapy. Cancer Immun 12, 14 (2012).
5. Gharwan, H. & Groninger, H. Kinase inhibitors and monoclonal antibodies in oncology: clinical implications. Nat Rev Clin Oncol 13, 209–227, https://doi.org/10.1038/nrclinonc.2015.213 (2016).
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