CKD-506, a novel HDAC6-selective inhibitor, improves renal outcomes and survival in a mouse model of systemic lupus erythematosus
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-35602-1.pdf
Reference72 articles.
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2. Almaani, S., Meara, A. & Rovin, B. H. Update on Lupus Nephritis. Clin. J. Am. Soc. Nephrol. 12, 825–835 (2017).
3. Wang, Y. et al. Amelioration of lupus-like autoimmune disease in NZB/WF1 mice after treatment with a blocking monoclonal antibody specific for complement component C5. Proc. Natl. Acad. Sci. USA 93, 8563–8568 (1996).
4. Yildirim-Toruner, C. & Diamond, B. Current and novel therapeutics in the treatment of systemic lupus erythematosus. J. Allergy. Clin. Immunol. 127, 303–312 (2011).
5. Choi, E. W., Lee, M., Song, J. W., Shin, I. S. & Kim, S. J. Mesenchymal stem cell transplantation can restore lupus disease-associated miRNA expression and Th1/Th2 ratios in a murine model of SLE. Sci. Rep. 6, 38237, https://doi.org/10.1038/srep38237 (2016).
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