Increased FUS levels in astrocytes leads to astrocyte and microglia activation and neuronal death
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-019-41040-4.pdf
Reference75 articles.
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2. Lagier-Tourenne, C. et al. Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs. Nat Neurosci 15, 1488–1497, https://doi.org/10.1038/nn.3230 (2012).
3. Errichelli, L. et al. FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons. Nat Commun 8, 14741, https://doi.org/10.1038/ncomms14741 (2017).
4. Kwiatkowski, T. J. Jr. et al. Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis. Science 323, 1205–1208, https://doi.org/10.1126/science.1166066 (2009).
5. Renton, A. E., Chio, A. & Traynor, B. J. State of play in amyotrophic lateral sclerosis genetics. Nat Neurosci 17, 17–23, https://doi.org/10.1038/nn.3584 (2014).
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