Author:
Jones Grant,Arias Diego,Nock Matthew
Abstract
AbstractSuicide is one of the leading causes of death amongst adolescents and decades of research have failed to curb suicide rates within this population. There is thus a need to better understand factors that correlate with adolescent suicidal thoughts and behaviors (STBs). MDMA/ecstasy and classic psychedelics represent two areas for exploration, as use of these substances has been associated with both increased and lowered odds of STBs. Thus, the goal of this study was to test the associations between MDMA/ecstasy and classic psychedelics (psilocybin, peyote, mescaline, LSD) and STBs in a nationally representative sample of U.S. adolescents. We tested these associations in a sample of adolescents aged 12–17 years old from the National Survey on Drug Use and Health (2004–2019) (N = 262,617) using survey-weighted multivariable logistic regression models. Lifetime psilocybin use was associated with lowered odds of lifetime suicidal thinking, planning, and attempts (aOR range 0.77–0.85). Conversely, LSD was associated with increased odds of these same outcomes (aOR range 1.20–1.35). MDMA/ecstasy, peyote, and mescaline did not share associations with STBs. Our study demonstrates that individual classic psychedelics share varying relationships to STBs among adolescents. Future cross-sectional and longitudinal studies are needed to further elucidate the link between classic psychedelic use and STBs in youth.
Publisher
Springer Science and Business Media LLC
Reference55 articles.
1. Curtin, S (2020) State suicide rates among adolescents and young adults aged 10–24 : United States, 2000–2018. In: CDC. https://stacks.cdc.gov/view/cdc/93667. Accessed 5 Jan 2022.
2. Hawton, K., Saunders, K. E. & O’Connor, R. C. Self-harm and suicide in adolescents. Lancet 379, 2373–2382 (2012).
3. Fox, K. R. et al. Interventions for suicide and self-injury: A meta-analysis of randomized controlled trials across nearly 50 years of research. Psychol. Bull. 146, 1117–1145 (2020).
4. Kothgassner, O. D., Robinson, K., Goreis, A., Ougrin, D. & Plener, P. L. Does treatment method matter? A meta-analysis of the past 20 years of research on therapeutic interventions for self-harm and suicidal ideation in adolescents. Bord. Personal. Disord. Emot. Dysregul. 7, 9 (2020).
5. Griffiths, R. R., Richards, W. A., McCann, U. & Jesse, R. Psilocybin can occasion mystical-type experiences having substantial and sustained personal meaning and spiritual significance. Psychopharmacology 187, 268–283 (2006).
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