Structural model of human dUTPase in complex with a novel proteinaceous inhibitor-Reference-Cited by-同舟云学术

Structural model of human dUTPase in complex with a novel proteinaceous inhibitor

Published:2018-03-12 Issue:1 Volume:8 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Nyíri Kinga,Mertens Haydyn D. T.^ORCID,Tihanyi Borbála,Nagy Gergely N.,Kőhegyi Bianka,Matejka Judit,Harris Matthew J.,Szabó Judit E.,Papp-Kádár Veronika,Németh-Pongrácz Veronika,Ozohanics Olivér^ORCID,Vékey Károly,Svergun Dmitri I.,Borysik Antoni J.,Vértessy Beáta G.

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-018-22145-8.pdf

Reference78 articles.

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2. Nyíri, K. & Vértessy, B. G. Perturbation of genome integrity to fight pathogenic microorganisms. Biochim. Biophys. Acta - Gen. Subj. 1861, 3593–3612 (2017).

3. Warner, H. R., Duncan, B. K., Garrett, C. & Neuhard, J. Synthesis and metabolism of uracil-containing deoxyribonucleic acid in Escherichia coli. J. Bacteriol. 145, 687–95 (1981).

4. Studebaker, A. W., Lafuse, W. P., Kloesel, R. & Williams, M. V. Modulation of human dUTPase using small interfering RNA. Biochem. Biophys. Res. Commun. 327, 306–310 (2005).

5. Merényi, G. et al. Cellular response to efficient dUTPase RNAi silencing in stable HeLa cell lines perturbs expression levels of genes involved in thymidylate metabolism. Nucleosides. Nucleotides Nucleic Acids 30, 369–90 (2011).

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