Electrophysiological properties of human beta-cell lines EndoC-βH1 and -βH2 conform with human beta-cells-Reference-Cited by-同舟云学术

Electrophysiological properties of human beta-cell lines EndoC-βH1 and -βH2 conform with human beta-cells

Published:2018-11-19 Issue:1 Volume:8 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Hastoy Benoît^ORCID,Godazgar Mahdieh,Clark Anne,Nylander Vibe,Spiliotis Ioannis,van de Bunt Martijn^ORCID,Chibalina Margarita V.,Barrett Amy,Burrows Carla,Tarasov Andrei I.,Scharfmann Raphael,Gloyn Anna L.^ORCID,Rorsman Patrik

Funder

Novo Nordisk postdoctoral fellowship run in partnership with the University of Oxford

Wellcome Trust

Medical Research Council

European union horizon 2020 Programme (T2D Systems) National Institute for health Research (NIHR) Oxford Biomedical Research Centre

Swedish Research Council National Institute for health Research (NIHR) Oxford Biomedical Research Centre

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-018-34743-7.pdf

Reference40 articles.

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2. Rorsman, P. & Ashcroft, F. M. Pancreatic b-cell electrical activity and insulin secretion: of mice and men. Physiological Reviews 98 (2018).

3. Hosker, J. P., Rudenski, A. S., Burnett, M. A., Matthews, D. R. & Turner, R. C. Similar reduction of first- and second-phase B-cell responses at three different glucose levels in type II diabetes and the effect of gliclazide therapy. Metabolism 38, 767–772 (1989).

4. Ashcroft, F. M. & Rorsman, P. Molecular defects in insulin secretion in type-2 diabetes. Rev Endocr Metab Disord 5, 135–142, https://doi.org/10.1023/B:REMD.0000021435.87776.a7 (2004).

5. Dimas, A. S. et al. Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity. Diabetes 63, 2158–2171, https://doi.org/10.2337/db13-0949 (2014).

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