Discovery of NV-5138, the first selective Brain mTORC1 activator
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-019-40693-5.pdf
Reference42 articles.
1. Wang, M. et al. Recent Insights into the Biological Functions of Sestrins in Health and Disease. Cell Physiol Biochem 43, 1731–1741, https://doi.org/10.1159/000484060 (2017).
2. Lee, J. H., Budanov, A. V. & Karin, M. Sestrins orchestrate cellular metabolism to attenuate aging. Cell Metab 18, 792–801, https://doi.org/10.1016/j.cmet.2013.08.018 (2013).
3. Lee, J. H. et al. Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies. Science 327, 1223–1228, https://doi.org/10.1126/science.1182228 (2010).
4. Park, H. W. et al. Hepatoprotective role of Sestrin2 against chronic ER stress. Nat Commun 5, 4233, https://doi.org/10.1038/ncomms5233 (2014).
5. Yang, Y. L. et al. SESN-1 is a positive regulator of lifespan in Caenorhabditis elegans. Experimental gerontology 48, 371–379, https://doi.org/10.1016/j.exger.2012.12.011 (2013).
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