Intra- and inter-individual metabolic profiling highlights carnitine and lysophosphatidylcholine pathways as key molecular defects in type 2 diabetes
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-019-45906-5.pdf
Reference60 articles.
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2. Roberts, L. D., Koulman, A. & Griffin, J. L. Towards metabolic biomarkers of insulin resistance and type 2 diabetes: progress from the metabolome. Lancet Diabetes Endocrinol. 2, 65–75 (2014).
3. Koves, T. R. et al. Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance. Cell Metab. 7, 45–56 (2008).
4. Prawitt, J., Caron, S. & Staels, B. Bile Acid Metabolism and the Pathogenesis of Type 2 Diabetes. Curr. Diab. Rep. 11, 160 (2011).
5. World Health Organization. Global report on diabetes. (World Health Organization, 2016).
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