The Specificity of EGF-Stimulated IQGAP1 Scaffold Towards the PI3K-Akt Pathway is Defined by the IQ3 motif
Author:
Funder
U.S. Department of Health & Human Services | National Institutes of Health
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-019-45671-5.pdf
Reference44 articles.
1. Lui, V. W. Y. et al. Frequent Mutation of the PI3K Pathway in Head and Neck Cancer Defines Predictive Biomarkers. Cancer Discov 3, 761–769, https://doi.org/10.1158/2159-8290.Cd-13-0103 (2013).
2. Pedrero, J. M. G. et al. Frequent genetic and biochemical alterations of the PI3-K/AKT/PTEN pathway in head and neck squamous cell carcinoma. Int J Cancer 114, 242–248, https://doi.org/10.1002/ijc.20711 (2005).
3. Courtney, K. D., Corcoran, R. B. & Engelman, J. A. The PI3K Pathway As Drug Target in Human Cancer. J Clin Oncol 28, 1075–1083, https://doi.org/10.1200/Jco.2009.25.3641 (2010).
4. Tan, X., Thapa, N., Sun, Y. & Anderson, R. A. A kinase-independent role for EGF receptor in autophagy initiation. Cell 160, 145–160, https://doi.org/10.1016/j.cell.2014.12.006 (2015).
5. Thapa, N. et al. The Hidden Conundrum of Phosphoinositide Signaling in Cancer. Trends. Cancer 2, 378–390, https://doi.org/10.1016/j.trecan.2016.05.009 (2016).
Cited by 29 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. In silico predicted compound targeting the IQGAP1-GRD domain selectively inhibits growth of human acute myeloid leukemia;Scientific Reports;2024-06-04
2. A p85 isoform switch enhances PI3K activation on endosomes by a MAP4- and PI3P-dependent mechanism;Cell Reports;2024-05
3. The mTORC2 signaling network: targets and cross-talks;Biochemical Journal;2024-01-25
4. Enhanced PI3K/Akt Signaling in Response to p85α Loss is Regulated by Endosomal PI3Kα and PI3P;2024-01-12
5. Epinephrine inhibits PI3Kα via the Hippo kinases;Cell Reports;2023-12
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3