Antiviral innate immune response in non-myeloid cells is augmented by chloride ions via an increase in intracellular hypochlorous acid levels
Author:
Funder
SR is financially supported by NHS Research Scotland (NRS), through NHS Lothian.
Medical Research Council (MRC)
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-31936-y.pdf
Reference28 articles.
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3. Wang, G. & Nauseef, W. M. Salt, chloride, bleach, and innate host defense. J Leukoc Biol 98, 163–172, https://doi.org/10.1189/jlb.4RU0315-109R (2015).
4. Chesney, J. A., Eaton, J. W. & Mahoney, J. R. Jr. Bacterial glutathione: a sacrificial defense against chlorine compounds. J Bacteriol 178, 2131–2135 (1996).
5. Winterbourn, C. C., Hampton, M. B., Livesey, J. H. & Kettle, A. J. Modeling the reactions of superoxide and myeloperoxidase in the neutrophil phagosome: implications for microbial killing. J Biol Chem 281, 39860–39869, https://doi.org/10.1074/jbc.M605898200 (2006).
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