Induced cross-resistance of BRAFV600E melanoma cells to standard chemotherapeutic dacarbazine after chronic PLX4032 treatment
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-37188-0.pdf
Reference48 articles.
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3. Garbe, C., Eigentler, T. K., Keilholz, U., Hauschild, A. & Kirkwood, J. M. Systematic review of medical treatment in melanoma: current status and future prospects. Oncologist 16, 5–24, https://doi.org/10.1634/theoncologist.2010-0190 (2011).
4. Plummer, R. et al. A phase II study of the potent PARP inhibitor, Rucaparib (PF-01367338, AG014699), with temozolomide in patients with metastatic melanoma demonstrating evidence of chemopotentiation. Cancer Chemother Pharmacol 71, 1191–1199, https://doi.org/10.1007/s00280-013-2113-1 (2013).
5. Tawbi, H. A. et al. Inhibition of DNA repair with MGMT pseudosubstrates: phase I study of lomeguatrib in combination with dacarbazine in patients with advanced melanoma and other solid tumours. Br J Cancer 105, 773–777, https://doi.org/10.1038/bjc.2011.285 (2011).
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