Untargeted metabolomics reveals a new mode of action of pretomanid (PA-824)
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-23110-1.pdf
Reference21 articles.
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3. Singh, R. et al. PA-824 kills nonreplicating Mycobacterium tuberculosis by intracellular NO release. Science 322, 1392–1395 (2008).
4. Dogra, M. et al. Comparative bioactivation of the novel anti-tuberculosis agent PA-824 in Mycobacteria and a subcellular fraction of human liver. Br. J. Pharmacol. 162, 226–236 (2011).
5. Overy, D. P. et al. Explanatory signal interpretation and metabolite identification strategies for nominal mass FIE-MS metabolite fingerprints. Nat. Protoc. 3, 471–485 (2008).
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