Transient AID expression for in situ mutagenesis with improved cellular fitness
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-27717-2.pdf
Reference67 articles.
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3. Petersen-Mahrt, S. K., Harris, R. S. & Neuberger, M. S. AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification. Nature 418, 99–103, https://doi.org/10.1038/nature00862 (2002).
4. Wang, L., Jackson, W. C., Steinbach, P. A. & Tsien, R. Y. Evolution of new nonantibody proteins via iterative somatic hypermutation. Proc Natl Acad Sci USA 101, 16745–16749, https://doi.org/10.1073/pnas.0407752101 (2004).
5. Ho, M., Nagata, S. & Pastan, I. Isolation of anti-CD22 Fv with high affinity by Fv display on human cells. Proc Natl Acad Sci USA 103, 9637–9642, https://doi.org/10.1073/pnas.0603653103 (2006).
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