Felis catus papillomavirus type-2 E6 binds to E6AP, promotes E6AP/p53 binding and enhances p53 proteasomal degradation
Author:
Funder
Ministero della Salute
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-35723-7.pdf
Reference35 articles.
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2. Wallace, N. A. & Galloway, D. A. Novel functions of the human papillomavirus E6 oncoproteins. Annu. Rev. Virol. 2, 403–423 (2015).
3. Martinez-Zapien, D. et al. Structure of the E6/E6AP/p53 complex required for HPV-mediated degradation of p53. Nature 529, 541–545 (2016).
4. Tanaka, T. I. & Alawi, F. Human papillomavirus and oropharyngeal cancer. Dent. Clin. North Am. 62, 111–120 (2018).
5. Altamura, G. et al. Transforming properties of Felis catus papillomavirus type 2 E6 and E7 putative oncogenes in vitro and their transcriptional activity in feline squamous cell carcinoma in vivo. Virology 496, 1–8 (2016).
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