Novel monoclonal antibody L2A5 specifically targeting sialyl-Tn and short glycans terminated by alpha-2

Novel monoclonal antibody L2A5 specifically targeting sialyl-Tn and short glycans terminated by alpha-2–6 sialic acids

Published:2018-08-15 Issue:1 Volume:8 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Loureiro Liliana R.^ORCID,Sousa Diana P.^ORCID,Ferreira Dylan,Chai Wengang,Lima Luís,Pereira Carina,Lopes Carla B.,Correia Viviana G.,Silva Lisete M.,Li Chunxia,Santos Lúcio Lara,Ferreira José Alexandre^ORCID,Barbas Ana^ORCID,Palma Angelina S.,Novo Carlos,Videira Paula A.^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-018-30421-w.pdf

Reference65 articles.

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4. Vasconcelos-dos-Santos, A. et al. Biosynthetic Machinery Involved in Aberrant Glycosylation: Promising Targets for Developing of Drugs Against Cancer. Front. Oncol. 5 (2015).

5. Marcos, N. T. et al. Role of the human ST6GalNAc-I and ST6GalNAc-II in the synthesis of the cancer-associated Sialyl-Tn antigen. Cancer Res. 64, 7050–7057 (2004).

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