The identification of molecular target of (20S) ginsenoside Rh2 for its anti-cancer activity

Author:

Wang Yu-Shi,Lin YingjiaORCID,Li He,Li Yang,Song Zhiguang,Jin Ying-Hua

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Reference33 articles.

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2. Zhu, J. H. et al. Suppression of the formation of sister chromatid exchanges by low concentrations of ginsenoside Rh2 in human blood lymphocytes. Cancer Research 55(6), 1221–3 (1995).

3. Xia, T. et al. Inhibition of autophagy potentiates anti-cancer property of 20(S)-ginsenoside Rh2 by promoting mitochondria-dependent apoptosis in human acute lymphoblastic leukaemia cells. Oncotarget (2016).

4. Oh, J. I. et al. Caspase-3-dependent protein kinase C delta activity is required for the progression of Ginsenoside-Rh2-induced apoptosis in SK-HEP-1 cells. Cancer Letters 230(2), 228–38 (2006).

5. Jin, Y. H. et al. Caspase 3-mediated Cleavage of p21WAF1/CIP1 Associated with the Cyclin A-Cyclin-dependent Kinase 2 Complex Is a Prerequisite for Apoptosis in SK-HEP-1 Cells. Journal of Biological Chemistry 275(39), 30256–63 (2000).

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