Author:
Park Young Hwan,Son Sei Wook,Han Sang Roc,Kim Hak Jun
Abstract
AbstractTo date, only a few clinical studies have investigated the differences between 2-octyl cyanoacrylate and n-octyl cyanoacrylate topical skin adhesives (TSAs). This study aimed to compare the outcomes of the two TSAs for wound closure after ankle fracture surgeries. Fifty-six patients were randomized to receive either a 2-octyl or n-octyl cyanoacrylate TSA. At 3 and 6 months after surgery, wound cosmetic outcomes were assessed using the Hollander Wound Evaluation Scale (HWES), and patient satisfaction for wound cosmesis was assessed using the visual analog scale (VAS) and 5-item Likert scale. Functional outcomes at 6 months after surgery were assessed using the Olerud–Molander Ankle Score (OMAS). Fifty-five patients completed the study protocol. Within the follow-up period, no differences were found between the two groups in terms of HWES, VAS, 5-item Likert scale, and OMAS. 2-octyl cyanoacrylate TSA and n-octyl cyanoacrylate TSA were comparable options for wound closure after ankle fracture surgeries in terms of wound cosmesis, patient satisfaction, and functional outcome.
Publisher
Springer Science and Business Media LLC
Reference32 articles.
1. Coover, H. W., Joyner, F. B., Sheare, T. H. & Wicker, T. H. Chemistry and performance of cyanoacrylate adhesives. J. Soc. Plast. Eng. 5, 413–417 (1959).
2. Singer, A. J., Quinn, J. V. & Hollander, J. E. The cyanoacrylate topical skin adhesives. Am. J. Emerg. Med. 26, 490–496 (2008).
3. Park, Y. H., Song, J. H., Choi, G. W. & Kim, H. J. Comparison of 2-octyl cyanoacrylate topical skin adhesive and simple interrupted nylon sutures for wound closure in ankle fracture surgery. Foot Ankle Int. 39, 1283–1289 (2018).
4. Dowson, C. C., Gilliam, A. D., Speake, W. J., Lobo, D. N. & Beckingham, I. J. A prospective, randomized controlled trial comparing n-butyl cyanoacrylate tissue adhesive (LiquiBand) with sutures for skin closure after laparoscopic general surgical procedures. Surg. Laparosc. Endosc. Percutan. Tech. 16, 146–150 (2006).
5. Lin, M., Coates, W. C. & Lewis, R. J. Tissue adhesive skills study: The physician learning curve. Pediatr. Emerg. Care 20, 219–223 (2004).