A repository of protein abundance data of drug metabolizing enzymes and transporters for applications in physiologically based pharmacokinetic (PBPK) modelling and simulation-Reference-Cited by-同舟云学术

A repository of protein abundance data of drug metabolizing enzymes and transporters for applications in physiologically based pharmacokinetic (PBPK) modelling and simulation

Published:2019-07-04 Issue:1 Volume:9 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Ladumor Mayur K.^ORCID,Thakur Aarzoo,Sharma Sheena,Rachapally Aravind,Mishra Sarang,Bobe Priyanka,Rao V. Kameswara,Pammi Praneetha,Kangne Hari,Levi David,Balhara Ankit,Ghandikota Sriram,Joshi Anupama,Nautiyal Vivek^ORCID,Prasad Bhagwat,Singh Saranjit

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-019-45778-9.pdf

Reference73 articles.

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2. Hartmanshenn, C., Scherholz, M. & Androulakis, I. P. Physiologically-based pharmacokinetic models: approaches for enabling personalized medicine. J. Pharmacokinet. Pharmacodyn. 43, 481–504 (2016).

3. Sato, M. et al. Quantitative modeling and simulation in PMDA: a Japanese regulatory perspective. CPT Pharmacometrics Syst. Pharmacol. 6, 413–415 (2017).

4. Shebley, M. et al. Physiologically based pharmacokinetic model qualification and reporting procedures for regulatory submissions: a consortium perspective. Clin. Pharmacol. Ther. 104, 88–110 (2018).

5. Bhatt, D. K. & Prasad, B. Critical issues and optimized practices in quantification of protein abundance level to determine interindividual variability in DMET proteins by LC-MS/MS proteomics. Clin. Pharmacol. Ther. 103, 619–630 (2018).

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