Non-invasive detection of adeno-associated viral gene transfer using a genetically encoded CEST-MRI reporter gene in the murine heart
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-22993-4.pdf
Reference37 articles.
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2. Pleger, S. T. et al. Heart failure gene therapy: The path to clinical practice. Circ. Res. 113, 792–809 (2013).
3. Kawase, Y., Ladage, D. & Hajjar, R. J. Rescuing the Failing Heart by Targeted Gene Transfer. J. Am. Coll. Cardiol. 57, 1169–1180 (2011).
4. Jessup, M. et al. Calcium upregulation by percutaneous administration of gene therapy in cardiac disease (CUPID): A phase 2 trial of intracoronary gene therapy of sarcoplasmic reticulum Ca2 + -ATPase in patients with advanced heart failure. Circulation 124, 304–313 (2011).
5. Greenberg, B. et al. Calcium upregulation by percutaneous administration of gene therapy in patients with cardiac disease (CUPID 2): A randomised, multinational, double-blind, placebo-controlled, phase 2b trial. Lancet 387, 1178–1186 (2016).
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