Characterization of membrane penetration and cytotoxicity of C9orf72-encoding arginine-rich dipeptides-Reference-Cited by-同舟云学术

Characterization of membrane penetration and cytotoxicity of C9orf72-encoding arginine-rich dipeptides

Published:2018-08-24 Issue:1 Volume:8 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Kanekura Kohsuke,Harada Yuichiro,Fujimoto Mao,Yagi Takuya,Hayamizu Yuhei,Nagaoka Kentaro^ORCID,Kuroda Masahiko

Funder

Japan Society for the Promotion of Science

Japan Agency for Medical Research and Development

Takeda Science foundation, Japan Intractable Diseases Research foundation, Tokyo biochemistry research foundation, The Ichiro Kanehara foundation.

Strategic Research Foundation Grant-aided Project for Private Universities from the Ministry of Education, Culture, Sports, Science and Technology of Japan

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-018-31096-z.pdf

Reference31 articles.

1. DeJesus-Hernandez, M. et al. Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS. Neuron 72, 245–256 (2011).

2. Mori, K. et al. The C9orf72 GGGGCC Repeat Is Translated into Aggregating Dipeptide-Repeat Proteins in FTLD/ALS. Science (80-). 339, 1335–1338 (2013).

3. Mizielinska, S. et al. C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins. Science (80-). 345, 1192–1194 (2014).

4. Kwon, I. et al. Poly-dipeptides encoded by the C9orf72 repeats bind nucleoli, impede RNA biogenesis, and kill cells. Science (80-). 345, 1139–1145 (2014).

5. Kanekura, K. et al. Poly-dipeptides encoded by the C9ORF72 repeats block global protein translation. Hum. Mol. Genet. 25, 1803–1813 (2016).

Cited by 49 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. C9orf72 polyPR interaction with the nuclear pore complex;Biophysical Journal;2024-08

2. Catechol‐Siderophore Mimics Convey Nucleic Acid Therapeutics into Bacteria;Angewandte Chemie International Edition;2024-03-11

3. Catechol‐Siderophore Mimics Convey Nucleic Acid Therapeutics into Bacteria;Angewandte Chemie;2024-03-11

4. Physiological and pathological effects of phase separation in the central nervous system;Journal of Molecular Medicine;2024-03-05

5. Opto-controlled C9orf72 poly-PR forms anisotropic condensates causative of TDP-43 pathology in the nucleus;2024-03-05