Elucidating the transactivation domain of the pleiotropic transcription factor Myrf
Author:
Funder
U.S. Department of Health & Human Services | National Institutes of Health
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-31477-4.pdf
Reference32 articles.
1. Emery, B. et al. Myelin gene regulatory factor is a critical transcriptional regulator required for CNS myelination. Cell 138, 172–185 (2009).
2. Bujalka, H. et al. MYRF is a membrane-associated transcription factor that autoproteolytically cleaves to directly activate myelin genes. Plos Biol 11, e1001625 (2013).
3. Li, Z. H., Park, Y. & Marcotte, E. M. A bacteriophage tailspike domain promotes self-cleavage of a human membrane-bound transcription factor, the myelin regulatory factor MYRF. Plos Biol 11, e1001624 (2013).
4. Senoo, H., Araki, T., Fukuzawa, M. & Williams, J. G. A new kind of membrane-tethered eukaryotic transcription factor that shares an auto-proteolytic processing mechanism with bacteriophage tail-spike proteins. J Cell Sci 126, 5247–5258 (2013).
5. Koenning, M. et al. Myelin gene regulatory factor is required for maintenance of myelin and mature oligodendrocyte identity in the adult CNS. The Journal of Neuroscience 32, 12528–12542 (2012).
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