Pharmacokinetic-Pharmacodynamic modelling of intracellular Mycobacterium tuberculosis growth and kill rates is predictive of clinical treatment duration
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-017-00529-6.pdf
Reference67 articles.
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3. Muliaditan, M., Davies, G. R., Simonsson, U. S., Gillespie, S. H. & Della Pasqua, O. The implications of model-informed drug discovery and development for tuberculosis. Drug Discov Today, doi: 10.1016/j.drudis.2016.09.004 (2016).
4. Hu, Y., Coates, A. R. & Mitchison, D. A. Sterilizing activities of fluoroquinolones against rifampin-tolerant populations of Mycobacterium tuberculosis. Antimicrobial agents and chemotherapy 47, 653–657 (2003).
5. Nuermberger, E. L. et al. Moxifloxacin-containing regimen greatly reduces time to culture conversion in murine tuberculosis. American journal of respiratory and critical care medicine 169, 421–426, doi: 10.1164/rccm.200310-1380OC (2004).
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