Early heme oxygenase 1 induction delays tumour initiation and enhances DNA damage repair in liver macrophages of Mdr2−/− mice
Author:
Funder
Deutsche Forschungsgemeinschaft
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-33233-0.pdf
Reference47 articles.
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2. Davis, G. L. et al. Hepatocellular carcinoma: management of an increasingly common problem. Proceedings 21, 266–280 (2008).
3. El-Serag, H. B. & Rudolph, K. L. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology 132, 2557–2576, https://doi.org/10.1053/j.gastro.2007.04.061 (2007).
4. Tebbi, A. et al. Deficiency of multidrug resistance 2 contributes to cell transformation through oxidative stress. Carcinogenesis 37, 39–48, https://doi.org/10.1093/carcin/bgv156 (2016).
5. Katzenellenbogen, M. et al. Multiple adaptive mechanisms to chronic liver disease revealed at early stages of liver carcinogenesis in the Mdr2-knockout mice. Cancer research 66, 4001–4010, https://doi.org/10.1158/0008-5472.CAN-05-2937 (2006).
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