Metformin attenuates the onset of non-alcoholic fatty liver disease and affects intestinal microbiota and barrier in small intestine-Reference-Cited by-同舟云学术

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Metformin attenuates the onset of non-alcoholic fatty liver disease and affects intestinal microbiota and barrier in small intestine

Published:2019-04-30 Issue:1 Volume:9 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Brandt Annette,Hernández-Arriaga Angélica,Kehm Richard,Sánchez Victor,Jin Cheng Jun,Nier Anika,Baumann Anja,Camarinha-Silva Amélia,Bergheim Ina

Funder

state of Baden-Württemberg

Bundesministerium für Bildung und Forschung

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-019-43228-0.pdf

Reference60 articles.

1. Younossi, Z. M. et al. Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes. Hepatology 64, 73–84, https://doi.org/10.1002/hep.28431 (2016).

2. Kirpich, I. A., Marsano, L. S. & McClain, C. J. Gut-liver axis, nutrition, and non-alcoholic fatty liver disease. Clin. Biochem. 48, 923–930, https://doi.org/10.1016/j.clinbiochem.2015.06.023 (2015).

3. Boursier, J. et al. The severity of nonalcoholic fatty liver disease is associated with gut dysbiosis and shift in the metabolic function of the gut microbiota. Hepatology 63, 764–775, https://doi.org/10.1002/hep.28356 (2016).

4. Miele, L. et al. Increased intestinal permeability and tight junction alterations in nonalcoholic fatty liver disease. Hepatology 49, 1877–1887, https://doi.org/10.1002/hep.22848 (2009).

5. Sellmann, C., Jin, C. J., Engstler, A. J., De Bandt, J. P. & Bergheim, I. Oral citrulline supplementation protects female mice from the development of non-alcoholic fatty liver disease (NAFLD). Eur. J. Nutr. 56, 2519–2527, https://doi.org/10.1007/s00394-016-1287-9 (2017).

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