Author:
Parvatkar Prakash T.,Smotkin Eugene S.,Manetsch Roman
Abstract
AbstractThe synthesis of tetracyclic indole alkaloid (±)-decursivine was accomplished using BINOL-phosphoric acid catalyzed tandem oxidative cyclization as a key step with (bis(trifluoroacetoxy)iodo)benzene (PIFA) as an oxidizing agent. This represents one of the shortest and highest yielding routes for the synthesis of (±)-decursivine from readily available starting materials.
Funder
National Institutes of Health
Publisher
Springer Science and Business Media LLC
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