Author:
Cao Yan,Dhahad Hayder A.,El-Shorbagy M. A.,Alijani Hajar Q.,Zakeri Mana,Heydari Abolfazl,Bahonar Ehsan,Slouf Miroslav,Khatami Mehrdad,Naderifar Mahin,Iravani Siavash,Khatami Sanaz,Dehkordi Farnaz Farzaneh
Abstract
AbstractIn this study, a simple and green strategy was reported to prepare bimetallic nanoparticles (NPs) by the combination of zinc oxide (ZnO) and copper oxide (CuO) using Sambucus nigra L. extract. The physicochemical properties of these NPs such as crystal structure, size, and morphology were studied by X-ray diffraction (XRD), field emission gun scanning electron microscopy (FEG-SEM), and transmission electron microscopy (TEM). The results suggested that these NPs contained polygonal ZnO NPs with hexagonal phase and spherical CuO NPs with monoclinic phase. The anticancer activity of the prepared bimetallic NPs was evaluated against lung and human melanoma cell lines based on MTT assay. As a result, the bimetallic ZnO/CuO NPs exhibited high toxicity on melanoma cancer cells while their toxicity on lung cancer cells was low.
Publisher
Springer Science and Business Media LLC
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