Author:
Joseph Jeff,Niemczak Christopher,Lichtenstein Jonathan,Kobrina Anastasiya,Magohe Albert,Leigh Samantha,Ealer Christin,Fellows Abigail,Reike Catherine,Massawe Enica,Gui Jiang,Buckey Jay C.
Abstract
AbstractTests of the brain’s ability to process complex sounds (central auditory tests) correlate with overall measures of neurocognitive performance. In the low- middle-income countries where resources to conduct detailed cognitive testing is limited, tests that assess the central auditory system may provide a novel and useful way to track neurocognitive performance. This could be particularly useful for children living with HIV (CLWH). To evaluate this, we administered central auditory tests to CLWH and children living without HIV and examined whether central auditory tests given early in a child’s life could predict later neurocognitive performance. We used a machine learning technique to incorporate factors known to affect performance on neurocognitive tests, such as education. The results show that central auditory tests are useful predictors of neurocognitive performance and perform as well or in some cases better than factors such as education. Central auditory tests may offer an objective way to track neurocognitive performance in CLWH.
Funder
National Institutes of Health
Publisher
Springer Science and Business Media LLC