The new X-ray/visible microscopy MAXWELL technique for fast three-dimensional nanoimaging with isotropic resolution

Author:

Kohmura Yoshiki,Yang Shun-Min,Chen Hsiang-Hsin,Takano Hidekazu,Chang Chia-Ju,Wang Ya-Sian,Lee Tsung-Tse,Chiu Ching-Yu,Yang Kai-En,Chien Yu-Ting,Hu Huan-Ming,Su Tzu-Ling,Petibois Cyril,Chen Yi-Yun,Hsu Cheng-Huan,Chen Peilin,Hueng Dueng-Yuan,Chen Shean-Jen,Yang Chi Lin,Chin An-Lun,Low Chian-Ming,Tan Francis Chee Kuan,Teo Alvin,Tok Eng Soon,Cai Xu Xiang,Lin Hong-Ming,Boeckl John,Stampfl Anton P.,Yamada Jumpei,Matsuyama Satoshi,Ishikawa Tetsuya,Margaritondo Giorgio,Chiang Ann-Shyn,Hwu Yeukuang

Abstract

AbstractMicroscopy by Achromatic X-rays With Emission of Laminar Light (MAXWELL) is a new X-ray/visible technique with attractive characteristics including isotropic resolution in all directions, large-volume imaging and high throughput. An ultrathin, laminar X-ray beam produced by a Wolter type I mirror irradiates the sample stimulating the emission of visible light by scintillating nanoparticles, captured by an optical system. Three-dimensional (3D) images are obtained by scanning the specimen with respect to the laminar beam. We implemented and tested the technique with a high-brightness undulator at SPring-8, demonstrating its validity for a variety of specimens. This work was performed under the Synchrotrons for Neuroscience—an Asia–Pacific Strategic Enterprise (SYNAPSE) collaboration.

Funder

Ministry of Science and Technology, Taiwan

Asian Office of Aerospace Research and Development

Higher Education Sprout Project, Ministry of Education & Ministry of Science and Technology, Taiwan

National University of Singapore

National University of Singapore - National Supercomputing Center, Singapore

RIKEN

École Polytechnique Fédérale de Lausanne

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

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