Characterizing the conformational landscape of MDM2-binding p53 peptides using Molecular Dynamics simulations
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-017-15930-4.pdf
Reference58 articles.
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3. Ventura, A. et al. Restoration of p53 function leads to tumour regression in vivo. Nature 445, 661–5 (2007).
4. Khoo, K. H., Hoe, K. K., Verma, C. S. & Lane, D. P. Drugging the p53 pathway: understanding the route to clinical efficacy. Nat. Rev. Drug Discov. 13, 217–36 (2014).
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