Abstract
AbstractTo investigate the diagnostic value of combined SWE, SMI, and B-mode US scores for distinguishing between benign and malignant masses. A total of 450 breast masses that underwent US-guided core needle biopsies were prospectively enrolled. The breast masses were assessed based on the BI-RADS and quantitative SWE and SMI parameters. The SWEmax, SWEratio, and SMIVI cutoff value were determined using Youden’s index by comparison to the pathological results. The BI-RADS categories were scored on a scale from 1 to 5, and SWEmax, SWEratio, and SMIVI were dichotomized based on each cutoff values (0 or 1). The combined scores (1 to 8) were calculated as the sum of the BI-RADS score and the quantitative scores and compared to the pathologic results using AUROC analysis. The cutoff values were 52.25 kPa for SWEmax, 5.03 for SWEratio, and 2.15% for SMIVI. In AUROC, the combined scores showed significantly better diagnostic performance compared to BI-RADS alone (p < 0.001). The combined score showed significantly increased than BI-RADS alone in specificity (p < 0.001) and accuracy (p < 0.001), but a sensitivity decreased without significance (p = 0.082). When a combined score cutoff value of 4 was used, the false negative rate was 2.7%. Using the combined score, 76.4% of the C4a lesions were considered benign also pathologically diagnosed as benign. The combined scores showed improved diagnostic performance in differentiating between benign and malignant breast masses, which could be helpful for determining a breast biopsy eligibility.
Publisher
Springer Science and Business Media LLC
Reference33 articles.
1. Mendelson, E. B. et al. ACR BI-RADS ultrasound. In ACR BI-RADS Atlas, Breast Imaging Reporting and Data System 5th edn (eds D’Orsi, C. J. et al.) 1–173 (American College of Raiology, 2003).
2. Lee, S. H. et al. Added value of shear-wave elastography for evaluation of breast masses detected with screening US imaging. Radiology 273, 61–69 (2014).
3. Liu, B. et al. Breast lesions: Quantitative diagnosis using ultrasound shear wave elastography—a systematic review and meta-analysis. Ultrasound Med. Biol. 42, 835–847 (2016).
4. Park, A. Y. et al. A prospective study on the value of ultrasound microflow assessment to distinguish malignant from benign solid breast masses: Association between ultrasound parameters and histologic microvessel densities. Korean J. Radiol. 20, 759–772 (2019).
5. Barr, R. G. et al. WFUMB guidelines and recommendations for clinical use of ultrasound elastography: Part 2: breast. Ultrasound Med. Biol. 41, 1148–1160 (2015).
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