Cyclosporine A binding to COX-2 reveals a novel signaling pathway that activates the IRE1α unfolded protein response sensor
Author:
Funder
Gouvernement du Canada | Canadian Institutes of Health Research
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-34891-w.pdf
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3. Hetz, C. The unfolded protein response: controlling cell fate decisions under ER stress and beyond. Nat Rev Mol Cell Biol 13, 89–102, https://doi.org/10.1038/nrm3270 (2012).
4. Groenendyk, J., Agellon, L. B. & Michalak, M. Coping with endoplasmic reticulum stress in the cardiovascular system. Annu Rev Physiol 75, 49–67, https://doi.org/10.1146/annurev-physiol-030212-183707 (2013).
5. Acosta-Alvear, D. et al. XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks. Mol Cell 27, 53–66, https://doi.org/10.1016/j.molcel.2007.06.011 (2007).
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