Author:
Horák Aleš,Allen Andrew E.,Oborník Miroslav
Abstract
AbstractEukaryotic complex phototrophs exhibit a colorful evolutionary history. At least three independent endosymbiotic events accompanied by the gene transfer from the endosymbiont to host assembled a complex genomic mosaic. Resulting patchwork may give rise to unique metabolic capabilities; on the other hand, it can also blur the reconstruction of phylogenetic relationships. The ornithine–urea cycle (OUC) belongs to the cornerstone of the metabolism of metazoans and, as found recently, also photosynthetic stramenopiles. We have analyzed the distribution and phylogenetic positions of genes encoding enzymes of the urea synthesis pathway in eukaryotes. We show here that metazoan and stramenopile OUC enzymes share common origins and that enzymes of the OUC found in primary algae (including plants) display different origins. The impact of this fact on the evolution of stramenopiles is discussed here.
Funder
Grantová Agentura České Republiky
European Regional Development Fund
Publisher
Springer Science and Business Media LLC
Reference36 articles.
1. Allen, A. E. et al. Evolution and metabolic significance of the urea cycle in photosynthetic diatoms. Nature 473, 203–207 (2011).
2. Smith, S. R. et al. Evolution and regulation of nitrogen flux through compartmentalized metabolic networks in a marine diatom. Nat. Commun. https://doi.org/10.1038/s41467-019-12407-y (2019).
3. Burki, F. et al. Untangling the early diversification of eukaryotes: A phylogenomic study of the evolutionary origins of Centrohelida, Haptophyta and Cryptista. Proc. Biol. Sci. 283, 20152802 (2016).
4. Strassert, J. F. H., Jamy, M., Mylnikov, A. P., Tikhonenkov, D. V. & Burki, F. New phylogenomic analysis of the enigmatic phylum telonemia further resolves the eukaryote tree of life. Mol. Biol. Evol. 36, 757–765 (2019).
5. Frickey, T. & Lupas, A. N. PhyloGenie: Automated phylome generation and analysis. Nucleic Acids Res. 32, 5231–5238 (2004).
Cited by
11 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献