Biochemical and genetic characterization of a novel metallo-β-lactamase from marine bacterium Erythrobacter litoralis HTCC 2594

Author:

Jiang Xia-Wei,Cheng Hong,Huo Ying-Yi,Xu LinORCID,Wu Yue-Hong,Liu Wen-Hong,Tao Fang-Fang,Cui Xin-Jie,Zheng Bei-Wen

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Reference66 articles.

1. Miraula, M., Whitaker, J. J., Schenk, G. & Mitic, N. Beta-Lactam antibiotic-degrading enzymes from non-pathogenic marine organisms: a potential threat to human health. J. Biol. Inorg. Chem. 20, 639–651 (2015).

2. Walsh, T. R., Toleman, M. A., Poirel, L. & Nordmann, P. Metallo-β-lactamases: the quiet before the storm? Clin. Microbiol. Rev. 18, 306–325 (2005).

3. Maltezou, H. C. Metallo-beta-lactamases in Gram-negative bacteria: introducing the era of pan-resistance? Int. J. Antimicrob. Agents. 33(405), e401–407 (2009).

4. Pfennigwerth, N. et al. Genetic and biochemical characterization of HMB-1, a novel subclass B1 metallo-beta-lactamase found in a Pseudomonas aeruginosa clinical isolate. J. Antimicrob. Chemother. 72, 1068–1073 (2017).

5. Zheng, F., Sun, J., Cheng, C. & Rui, Y. Molecular characteristics of carbapenem-resistant gram-negative bacteria in southern China. Microb. Drug. Resist. 21, 178–185 (2015).

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