X-Ray snapshots of a pyridoxal enzyme: a catalytic mechanism involving concerted [1,5]-hydrogen sigmatropy in methionine γ-lyase
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-017-05032-6.pdf
Reference39 articles.
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2. Sato, D. & Nozaki, T. Methionine gamma-lyase: the unique reaction mechanism, physiological roles, and therapeutic applications against infectious diseases and cancers. IUBMB Life. 61, 1019–1028 (2009).
3. Yoshimura, M. et al. Formation of methyl mercaptan from l-methionine by Porphyromonas gingivalis. Infect. Immun. 68, 6912–6916 (2000).
4. Rébeillé, F. et al. Methionine catabolism in Arabidopsis cells is initiated by a γ-cleavage process and leads to S-methylcysteine and isoleucine syntheses. Proc. Natl. Acad. Sci. USA 103, 15687–15692 (2006).
5. Song, H., Xu, R. & Guo, Z. Identification and characterization of a methionine γ-lyase in the calicheamicin biosynthetic cluster of Micromonospora echinospora. ChemBioChem. 16, 100–109 (2014).
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