Hepatocellular carcinoma-targeting oncolytic adenovirus overcomes hypoxic tumor microenvironment and effectively disperses through both central and peripheral tumor regions
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-20268-6.pdf
Reference59 articles.
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3. Llovet, J. M., Burroughs, A. & Bruix, J. Hepatocellular carcinoma. Lancet 362, 1907–1917, https://doi.org/10.1016/S0140-6736(03)14964-1 (2003).
4. Zhuang, P. Y. et al. Peritumoral Neuropilin-1 and VEGF receptor-2 expression increases time to recurrence in hepatocellular carcinoma patients undergoing curative hepatectomy. Oncotarget 5, 11121–11132 (2014).
5. Kirn, D. Oncolytic virotherapy for cancer with the adenovirusdl1520 (Onyx-015): results of phase I and II trials. Expert opinion on biological therapy 1, 525–538, https://doi.org/10.1517/14712598.1.3.525 (2001).
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