Author:
Zalnezhad Erfan,Musharavati F.,Chen Tianyi,Jaber Fadi,Uzun Kaan,Chowdhury Muhammad E. H.,Khandakar Amith,Liu Junxing,Bae S.
Abstract
AbstractIn this study, a combination of reverse microemulsion and hydrothermal techniques were used to synthesize HA. A hydrothermal method was used to synthesize HA/TiO2/CNT nanocomposite powders. Cold and hot isostatic pressing techniques were used to fabricate tablet-shaped samples. To investigate the biocompatibility and tribo-mechanical properties of HA/TiO2 and HA/TiO2/CNTs, four samples were prepared with different percentages of CNTs, namely, HA/TiO2 (S0), HA/TiO2/CNT (S1.0), HA/TiO2/CNT (S2.0), and HA/TiO2/CNT (S3.0). The microstructure and morphology of the HA/TiO2/CNTs were characterized by transmission electron microscopy, scanning electron microscopy, energy-dispersive X-ray spectroscopy, and X-ray diffraction. Hardness test results show that S3.0 displayed the highest surface hardness (285 HV) compared to other samples. The wear rate of HA/TiO2/CNT with the highest CNT content showed a decrease compared with those of the other samples. The results from nanoindentation tests showed that Young’s modulus of the S3.0 sample was 58.1% greater than that of the S0 sample. Furthermore, the human MDA-MB-231 cell line demonstrated good binding to the surface of the samples in the in-vitro biocompatibility evaluation of the HA/TiO2/CNT composites.
Funder
This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government
Publisher
Springer Science and Business Media LLC
Reference53 articles.
1. Li, J. & Hastings, G. W. In Handbook of Biomaterial Properties (eds Murphy, W., Black, J. & Hastings, G.) 339–352 (Springer New York, New York, 2016).
2. White, A. A., Best, S. M. & Kinloch, I. A. Hydroxyapatite-carbon nanotube composites for biomedical applications: A review. Int. J. Appl. Ceram. Technol. 4, 1–13. https://doi.org/10.1111/j.1744-7402.2007.02113.x (2007).
3. Ahn, E. S., Gleason, N. J., Nakahira, A. & Ying, J. Y. Nanostructure processing of hydroxyapatite-based bioceramics. Nano Lett. 1, 149–153. https://doi.org/10.1021/nl0055299 (2001).
4. Heimann, R. B. Classic and Advanced Ceramics: From Fundamentals to Applications (Wiley, New York, 2010).
5. Patel, N. R. & Gohil, P. P. A review on biomaterials: Scope, applications & human anatomy significance. Int. J. Emerg. Technol. Adv. Eng. 2, 91–101 (2012).
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