A receptor dependent-4D QSAR approach to predict the activity of mutated enzymes
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-017-06625-x.pdf
Reference60 articles.
1. Chen, R., Greer, A. & Dean, A. M. Redesigning secondary structure to invert coenzyme specificity in isopropylmalate dehydrogenase. Proc Natl Acad Sci USA 93, 12171–12176 (1996).
2. Hurley, J. H., Chen, R. & Dean, A. M. Determinants of cofactor specificity in isocitrate dehydrogenase: structure of an engineered NADP+–> NAD+ specificity-reversal mutant. Biochemistry 35, 5670–5678 (1996).
3. Chen, R. A general strategy for enzyme engineering. Trends Biotechnol 17, 344–345 (1999).
4. Stemmer, W. P. C. DNA shuffling by random fragmentation and reassembly: in vitro recombination for molecular evolution. Proc Natl Acad Sci USA 91, 10747–10751 (1994).
5. Kuchner, O. & Arnold, F. H. Directed evolution of enzyme catalysts. Trends Biotechnol 15, 744–749 (1997).
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