Author:
Zhang Xi,Ni Shu-juan,Wang Xiao-hong,Huang Dan,Tang Wei
Abstract
AbstractThe objective of this study was to illustrate the clinical, CT, MRI, and 18F-FDG PET/CT features of adult pancreatoblastoma, an extremely rare disease. In this study, the clinical and imaging features of seven adult patients with pathologically confirmed pancreatoblastoma were retrospectively analyzed. The following parameters were evaluated: size, location, shape, margination, solid-cystic ratio, CT attenuation values or signal intensity and contrast enhancement pattern. We also analyzed whether abnormal FDG uptake occurred during 18F-FDG PET/CT imaging. All seven patients were male (mean age 45 years; range 22–65 years). Six tumors were irregular in shape, exogenous, and grew outward from the pancreatic parenchyma, similar to branches growing from a tree trunk (85.7%). The tumor margins were clear in five patients (71.4%), and three tumors (42.9%) were encapsulated. Six tumors (71.4%) were solid, with homogeneous enhancement observed on contrast-enhanced CT and MRI. Dynamic-enhanced CT and MRI showed progressive enhancement for all tumors. On 18F-FDG PET/CT, one tumor exhibited abnormal FDG uptake, and two tumors exhibited no abnormal uptake (66.7%). In conclusion, adult pancreatoblastoma most commonly occurs in male patients, and it usually appears as an exophytic, irregular, and hypovascular mass with well-defined margins and progressive enhancement on CT and MRI. This type of tumor always grows out of the parenchyma of the pancreas, similar to branches growing outward from a tree trunk.
Funder
National Natural Science Foundation of China
Natural Science Foundation of Shanghai
Publisher
Springer Science and Business Media LLC
Reference35 articles.
1. Argon, A., Çelik, A., Öniz, H., Özok, G. & Barbet, F. Y. Pancreatoblastoma, a rare childhood tumor: A case report. Turk. Patol. Derg. 33(2), 164–167 (2017).
2. Dhebri, A. R. et al. Diagnosis, treatment and outcome of pancreatoblastoma. Pancreatology 4(5), 441–453 (2004).
3. Imamura, A. et al. Pancreatoblastoma in an adolescent girl: Case report and review of 26 Japanese cases. Eur. J. Surg. 164(4), 309–312 (1998).
4. Zhang, D. et al. Pancreatoblastoma in an adult. Indian J. Pathol. Microbiol. 58(1), 93–95 (2015).
5. Du, E. et al. Ampullary pancreatoblastoma in an elderly patient: A case report and review of the literature. Arch. Pathol. Lab. Med. 127(11), 1501–1505 (2003).
Cited by
6 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献