Fenugreek Compound (N55) Lowers Plasma Glucose through the Enhancement of Response of Physiological Glucagon-like peptide-1
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-017-12290-x.pdf
Reference37 articles.
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2. Nadkarni, P., Chepurny, O. G. & Holz, G. G. Regulation of Glucose Homeostasis by GLP-1. Prog. Mol. Biol. Transl. Sci. 121, 23–65, https://doi.org/10.1016/b978-0-12-800101-1.00002-8 (2014).
3. Deacon, C. F. Circulation and degradation of GIP and GLP-1. Horm. Metab. Res. 36, 761–765, https://doi.org/10.1055/s-2004-826160 (2004).
4. Drucker, D. J. et al. Exenatide once weekly versus twice daily for the treatment of type 2 diabetes: a randomised, open-label, non-inferiority study. Lancet 372, 1240–1250, https://doi.org/10.1016/S0140-6736(08)61206-4 (2008).
5. Donath, M. Y. & Burcelin, R. GLP-1 effects on islets: hormonal, neuronal, or paracrine. Diabetes care 36(Suppl 2), S145–148, https://doi.org/10.2337/dcS13-2015 (2013).
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1. Medicinal Properties of Fenugreek: A Review;The Open Biology Journal;2023-03-31
2. Phytochemicals modulate pancreatic islet β cell function through glucagon-like peptide-1-related mechanisms;Biochemical Pharmacology;2022-03
3. Total synthesis and absolute structure of N55, a positive modulator of GLP-1 signaling;Organic & Biomolecular Chemistry;2020
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