Vps34/PI3KC3 deletion in kidney proximal tubules impairs apical trafficking and blocks autophagic flux, causing a Fanconi-like syndrome and renal insufficiency
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-32389-z.pdf
Reference64 articles.
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3. Vallon, V. et al. SGLT2 mediates glucose reabsorption in the early proximal tubule. Journal of the American Society of Nephrology: JASN 22, 104–112, https://doi.org/10.1681/ASN.2010030246 (2011).
4. Delacour, D., Salomon, J., Robine, S. & Louvard, D. Plasticity of the brush border - the yin and yang of intestinal homeostasis. Nature reviews. Gastroenterology & hepatology 13, 161–174, https://doi.org/10.1038/nrgastro.2016.5 (2016).
5. He, P., Zhao, L., No, Y. R., Karvar, S. & Yun, C. C. The NHERF1 PDZ1 domain and IRBIT interact and mediate the activation of Na+/H+ exchanger 3 by ANG II. American journal of physiology. Renal physiology 311, F343–351, https://doi.org/10.1152/ajprenal.00247.2016 (2016).
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