Ouabagenin is a naturally occurring LXR ligand without causing hepatic steatosis as a side effect
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-20663-z.pdf
Reference63 articles.
1. Blaustein, M. P. et al. The pump, the exchanger, and endogenous ouabain: signaling Mechanisms That Link Salt Retention to Hypertension. Hypertension 53, 291–2984 (2009).
2. Blaustein, M. P. Sodium ions, calcium ions, blood pressure regulation, and hypertension: a reassessment and a hypothesis. Am. J. Physiol. 232, C165–C173 (1977).
3. Pierre, S. V. & Xie, Z. The Na,K-ATPase Receptor Complex: Its Organization and Membership. Cell. Biochem. Biophy.s 46, 303–316 (2006).
4. Xie, Z. & Cai, T. Na+-K+-ATPase-mediated signal transduction: from protein interaction to cellular function. Mol. Interv. 3, 157–168 (2003).
5. Ogawa, H., Shinoda, T., Cornelius, F. & Toyoshima, C. Crystal structure of the sodium-potassium pump with bound potassium and ouabain. Proc. Natl. Acad. Sci. 106, 13742–13747 (2009).
Cited by 17 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. The Composition and Biochemical Properties of Strophantus (Apocynaceae), with a Focus on S. sarmentosus;Molecules;2024-06-14
2. Semisynthesis of natural products at room temperature;Semisynthesis of Bioactive Compounds and their Biological Activities;2024
3. Therapeutic effect of ouabagenin, a novel liver X receptor agonist, on atherosclerosis in nonalcoholic steatohepatitis in SHRSP5/Dmcr rat model;Canadian Journal of Physiology and Pharmacology;2023-09-01
4. Flindissone, a Limonoid Isolated from Trichilia prieuriana, Is an LXR Agonist;Journal of Natural Products;2023-08-01
5. In Silico Pharmacokinetic Profiling of the Identified Bioactive Metabolites of Pergularia tomentosa L. Latex Extract and In Vitro Cytotoxic Activity via the Induction of Caspase-Dependent Apoptosis with S-Phase Arrest;Pharmaceuticals;2022-09-09
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3